The Hiace entered the fifth generation in August 2004 in its first full model change in 15 years. Reflecting the polarization between the increasingly luxurious 1-box wagon and practical commercial van models that became apparent in the previous generation, the Super Custom wagon was spun off and integrated with the Alphard line (announced in May 2002). All models with a body length of 4.7 m or longer were fitted with a wide-body coach measuring 1,880 mm in width, which made vans the only Hiace models still classified in the "4 number" category. The body variations included a long standard-width body with a standard/high roof, a long and wide body with a medium roof, and a super-long and wide body with a high roof.

The Hiace wagon and van were popular among wide range of users, as these vehicles could be used not only for cargo transportation but also as campers and for carrying large leisure equipment.